Well there are a few more options:
-pills: sublingual intake of bioidentical micronized estrogen is supposed to be less straining on the liver. Spreading the daily dose in a few small doses instead of two big ones might help keep levels more steady, instead of highs and lows, which might affect mood in a pms like way.
-patches: the vivelle patches are said to be small and stick well.
Skins are different so reaction is individual. One possibility is to combine one patch with pills. The patch to keep levels steady.
-gels: quite convenient with intake
-injections: with biweekly injections there might be a low after 10 days. With weekly injections levels are more steady.
-implants: steady levels and no hassle.
https://www.susans.org/forums/index.php/topic,192044.msg1713877.html#msg1713877With implants and injections a form of hrt is possible where the estro levels are driven well into the female range and the testo levels down into the female range, without anti androgen.
Bioidentical progesterone might compliment estrogen.
It might help with mood, with breast development, even out some side effects of estrogen and has some anti androgen effects.
https://www.susans.org/forums/index.php/topic,192953.msg1733564.html#msg1733564