We tend to get it worst but it happens for CIS as well. Something as simple a marrying the wrong person or going into the wrong profession can cause family issues like this. I am a bit on the stubborn side and I am willing to stick it out and see if I can win them over. It's not an easy path to take but in the long run it can produce more desirable results.
I had to move to where I could receive better treatment and while I had a better income, my living expenses went way up for food and an apartment. My transition may have been slowed some by the fact I couldn't accumulate money as fast and when unemployment, I did't have close family support.
At some point, everybody you know will have to know about you or they will have to be eliminated from your life. When you make that decision is up to you but you might want to start thinking about it.