When I first started, my doctor started me out with a monthly injection for the first 3 months. It was not long acting T, it was the "normal" cypionate. The last week and a half of those months were absolutely miserable. After that first 3 months, I went to every other week. I didn't experience any negative effects with the every other week, but after about a year, I went to weekly (by choice) and have been much happier with that.
I had a friend go through the same doctor about a year after I did and he didn't start out with that "half dose" monthly schedule. I think that tends to be a method that is on its way out as I don't think there have been any studies that showed that starting at a half dose provides any advantage unless the individual wants to start out slower.
I will say that other than being a little sluggish at the end of those monthly cycles, I didn't see any negative impact. I have still seen a lot of changes and they happened fast for me.
But I agree with everything said above that it really does depend on the formulation. Some are intended to last much longer than others.