If indeed there was a cream that worked for maintaining youth, trust me, it would have already been found out by women through word of mouth and that cream in particular with that set of ingredients would have eventually been reproduced by other companies after the patent expired. No such cream, sadly. Indeed, surgery can help but I personally think the safest, most cost-effective and natural approach to slow down ageing is sex hormones (but due to fears related to that famous study, is more rarely prescribed these days), low levels of stress AND genetics. Malnutrition can accelerate ageing, perhaps excess carbs and too much sun exposure, of course...don't go to tanning salons...super nice short-term but long-term, awful (+ skin cancer).