Your Endo probably prescribed you conjugated E or Ethinilestradiol (the later is especially troublesome) since I doubt someone could push the dosage of estradiol valerate high enough to damage the liver especially if taken by injection, though with estradiol Cypionate, there would be slight chance since its more concentrated enabling much higher dosages. Estradiol is basically the natural female hormones and pregnant women have massive amounts with little adverse toxicity on the liver. The problem with ethinilestradiol is that its very difficult to break down and at a high dose creates a lot of bad byproducts when its metabolised by the liver.
Using estrogen alone to push down T levels is not really done anymore, because endo's used ethinilestradiol to do it and the result was a lot of DVT and in rarer cases liver problems. Using estradiol would not cause this problem, but doctors prefer to not relly only estrogen to do the job. The advantage of spiro is that it blocks both production of T at the testes and at the T receptor, so its action is quicker.
As for progesterone, usually if its given, its not given immediatly because it needs breast tissue to work on and it conteracts the effects of estrogen and since people start with lower doses of estrogen, you don't want that. After 6-12 months, you can add it. In GG's progesterone arrives when the menses start, that's 2 years at least after puberty started and breast started growing, so getting progesterone later seems to be how its done in nature.
