panic attacks and anxiety

[Rachael]

Have any of you ever experienced panic attacks and anxiety while on E. I currently inject E valerate once every two weeks and have been on E now for about 4 months, recently I had a severe bout with panic attacks and massive anxiety one week prior to my scheduled dosage. I am just trying to figure out why this happened since I have never had panic attacks before. I will be talking to my endo but just trying to see if anyone else has had anything similar.

[calicarly]

I haven't personally but I know of a girl who did, in the end she went off injectables and went on to a low oral dose and she says she feels much better these days and actually feels more benefits from the estradiol at a lower dose and no side effects. Seems like a rare thing for people to have adverse effects of e but it can happen.

[KayXo]

Have any of you ever experienced panic attacks and anxiety while on E. I currently inject E valerate once every two weeks and have been on E now for about 4 months, recently I had a severe bout with panic attacks and massive anxiety one week prior to my scheduled dosage. I am just trying to figure out why this happened since I have never had panic attacks before. I will be talking to my endo but just trying to see if anyone else has had anything similar.

Contraception. 1980 Apr;21(4):415-24.

"The average duration of elevated estrogen levels was shortest in the benzoate group (4-5 days) followed by the valerate (7-8 days)"

The reason is there is too much an interval between injections so levels drop too much. You could try asking your doctor to reduce interval to weekly. I inject every 5 days.