General Population acceptance depends very much on geographic area. I live in Washington State. As a whole, I never get any inkling of not being accepted in the Seattle area. There are people in all areas, including where I live, that like to adhere to traditional values and concepts of what makes a man and what makes a woman. But there is something about the West Coast mentality in general I think, and perhaps mostly centered around the metropolitan areas such as Vancouver BC, Seattle WA, Portland OR, and of course San Francisco that as a whole cares less about traditional gender roles and but more about character content as a whole...
I know by the vibe that I get out and about in the general Western Washington area when I am in public as a very happy and content non-binary gender role person dressed in full women's clothes because it is is my comfort zone, people do not seem to care much to focus on what plumbing I have had since birth, but more about my general warmth and openness.
Is this the West Coast? I don't know. But I like living where I do.