It depends on your goal. Are you trying to go out of the house and pass or are you wanting the most feminine look possible?
Falsies do create a very feminine and dramatic look.
Here in the Pacific Northwest a more natural look is the style and you don't see falsies on too many women. So I don't wear them - it would seem out-of-place and draw attention. I wear mascara (not the waterproof kind). It comes off with the foaming face wash that I use.