I've been on a starter dose of estradiol patches for a few weeks now, and up to this point, i've been placing them on my upper thigh, because that area is fairly smooth. However, the instructions in the box state that the best places are on the lower abdomen (below the waist on the right or left sides) or on the upper buttock (also right or left side).
Does it really matter? Does the estradiol absorb better on the abdomen or buttock than on the thighs?
Laura