What delivery methods are you prescribed for Estrogen?

[Rikigirl]

Hi everyone using Estrogen. I was interested in how most of us take our Estrogen as there is some research on the effects on the liver, and more recent research on which ones are best for breast growth!

[Ellement_of_Freedom]

I have an implant and take a daily oral dosage. Noticed my breasts are growing more at the moment, but I have no idea if that's because of how I take E.


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[Rikigirl]

Thanks Ellement!

Did you start on both together, or one first?
BTW great songwriter, Alicia Keys

[kaitylynn]

From what I have witnessed, patches, injection and implant seem to give some great results with pills being a hit or miss.  There is just so much to how our bodies change with steady inputs, that it is really hard to say.  We are each so different genetically.

My endo told me to look at clinical development instead of chasing numbers.  She had seen great results using patches and I have to say that I have loved the development I have received!  I started a 36A and am now a 36C in 15 months.  For that, my E levels never get above 110.

[SarahElizabeth1981]

I just started and I am using the patch. so far I have noticed some nice changes in my chest. The fat accumulation started pretty fast. More recently my nipples have risen and the entire breast has gotten a lot more sensitive. still pretty flat and I would say not enough to fill a cup. So I won't even say I'm an A or anything. As I'm just over a month though I'm pretty happy so far.

[Thessa]

I started with gel but after a few months I switched to suppositories. I feel better and also my breast development is more noticeable.

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[Harley Quinn]

more recent research on which ones are best for breast growth!

I can't say that I have ever seen research on which method provides best breast growth. Do you have a link?

[Michelle_P]

My endo told me to look at clinical development instead of chasing numbers.  She had seen great results using patches and I have to say that I have loved the development I have received!  I started a 36A and am now a 36C in 15 months.  For that, my E levels never get above 110.

Yup.  I've been on HRT 7 months now, spironolactone pills and estradiol via multiple patches.  I've never had an estradiol reading above 50 pg/mL, the lower limit for sensitivity for the particular lab test involved.

In spite of this, the breasts are aching, areolae puffy, and I'm a solid 34B, lifting the center of the bra well off the sternum now. (I gained width for a while, now I'm getting pointy again. )

The E is definitely in my system somewhere, doing it's thing.  I'd like to believe I have hungry, hungry receptors busily sucking down the serum levels.



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[Harley Quinn]

I keep hearing numbers like 34 and 36... wow you girls are "skinny!". LOL!

[Ellement_of_Freedom]

Thanks Ellement!

Did you start on both together, or one first?
BTW great songwriter, Alicia Keys

Yes I was on oral dosage only first. With the implant came less mood swings which is great, again I'm not sure if it's the reason why my breasts are growing more.

Good to see another Keys fan.

[Rikigirl]

Hi Harley Quinn,

The research was done and published by the European Endocrine society! I have been told I am not at high enough level to post links by the moderators, but the study is "Effects of oral and transdermal estrogen on IGF1, IGFBP3, IGFBP1, serum lipids, and glucose in patients with hypopituitarism during GH treatment: a randomized study". It is heavy reading but it is referenced in good page called "Hormonal Breast enhancement" which is a little easier to read on Wikipedia. A search engine should find them for you.

Yes I would love to be 34 or 36, try 38 or 40 for me! T and genetics hits some of us harder.

I hope this helps!

Hugs Riki

[Rikigirl]

Hi Ellement,

From the research that could be the reason! This is the basics of it;

The research done on oral Estrogen indicates it's not as smooth and even delivery as patches, and it does make the liver do more work! These are not as important as the last issue which is that oral Estrogen can reduce Insulin Growth Factor 1 (IGF-1) by 15-40% which is produced by the liver. The IGF-1 levels are very high in teenage girls going through puberty and their teenage years. Once we reach our 20's it gets lower, and lower again as we get older. This helps the breasts to grow so quickly in cis girls teenage years and researchers now suspect this is why mtf transsexuals have smaller breasts than their cis relatives.

Hugs Riki

[DuchessBianca]

Would kill to switch to IM but doctor won't let me due to the shortage and don't believe cypionate is supported where I go so just Sublingual tablets multiple times daily T_T I'll just have to continue to "Harrass" my doctor every month and maybe one day he'll give me the good news >_<

I keep hearing numbers like 34 and 36... wow you girls are "skinny!". LOL!

Sitting here at 42 something with about about 15-20 pounds I could lose before going to an unhealthy weight for my frame/height. If I ever break into the 30's I'd cry for joy T_T

[jentay1367]

Estradiol Cypionate I.M.

Breasts? Hmmmmm.....a 38AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA....and they hurt anyway, thanks Mom.

[AnonyMs]

I use implants but top it up a bit with gel towards the end.

[JoanneB]

When we did an informal comparison at my TG Support group the result was a vast YMMV. Some women went through several types of E and various delivery methods before finding one that worked best all around.

Just proves once again we are not all the same. Every body is different

[noleen111]

I started with the injection and got quick results.. I had A cup breasts at 1 month and B cup at 3 months. I also began to feminize quite quickly. After my injections I was moody for a day or so. After my first two or 3 injections I even got some morning sickness. 

After SRS I started with the implants. IT does regulate my e levels better and I am not so moody after my implant is inserted.

[Harley Quinn]

I remember this article. I saw it more as a study on IGF1 and HGH, but still quite a good read! Thanks.

[Rikigirl]

Thanks everyone for your responses! It has been interesting to see that many endocrinologists are prescribing less pills and more 'automated' delivery systems. I use multiple patches and find it works well for me although occasionally one will not stay on well!

Riki

[Nora Kayte]

Implanted pellets for Estrodiol. Biodentical from a compounding pharmacy for progesterone. And pills for spiro. reminds me I'm out of spiro. Crap.