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Failed progesterone and the battle continues...

Started by Harley Quinn, February 27, 2017, 01:49:04 PM

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JeanetteLW

Quote from: ainsley on May 02, 2017, 11:31:54 AM
I am not ashamed about it:  I self medicated completely for several years.  I supplementally self medicate now even though I am under a doctor's care for my HRT.  When they don't listen and will not do what I want, I take action if their reasons are not logical.  My body, free country, my transition.  :)  My labs are always spot on...

I could agree and I sympathize with you but like I said, "I'm trying to be a good girl" I'm just getting started and want to give him a chance.  This will be only my second lab series. Well see where I am and go from there. He knows my desires and I'll remind him again after the results are in and see what he says.

   Hugs,
      Laurie
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LexiDreamer

Quote from: ainsley on May 02, 2017, 09:39:17 AM
I have not, but KayXo has and I would recommend her advice regarding that.  Progesterone definitely increased my libido and my T levels are null (reference ranges are for women...I am post-op):

Testoster Free
0.16 ng/dL
Reference Range: 0.06-0.95

Testoster Tot
10 ng/dL
Reference Range: 8-60

Thanks Ainsley!

I thought it strange that she had me dial back my Spiro for my T being at 25 ng/dL.

One more question please...

Do you cycle the Prometrium or take it every day?

*** Any suggestions I make should never be used as a substitute for licensed medical advice ***
*** All of my personal pharmaceutical experiences I share, have been explicitly supervised by a licenced medical professional ***
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ainsley

I don't cycle.  I take it daily with food. 
I have recently begun adding inject-able progesterone to my regimen, too.  Very much liking the effects from that.  My nails stopped peeling and splitting, my hair is healthier, my libido is even better, and my hips are getting padding, albeit minor.  I have a voracious appetite, gain weight easily, and my workouts aren't as easy to get through, but, hey, that is what girls battle, right?
Some people say I'm apathetic, but I don't care.

Wonder Twin Powers Activate!
Shape of A GIRL!
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KayXo

Quote from: ainsley on May 03, 2017, 09:14:38 AM
I don't cycle.  I take it daily with food.

+ 1

QuoteI have recently begun adding inject-able progesterone to my regimen, too.

Injectable progesterone needs to be injected daily or at the very least every 2 days because its half-life is very short. On the other hand, hydroxyprogesterone caproate, another relatively safe progestogen can be injected less frequently (weekly to biweekly). FYI, for others. I know you know Ainsley. :)

Quote from: LexiDreamer on May 03, 2017, 08:56:07 AMI thought it strange that she had me dial back my Spiro for my T being at 25 ng/dL.

I don't think it is. Some T may be needed for some for energy, well-being, etc. BUT, some also do well on very low T so it depends. I think it best that a doctor adjusts according to the patient's feedback (how they feel, overall feminization) rather than numbers. Did you tell her things were alright for you on this dose?
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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LexiDreamer

#44
Well, my total Testosterone level was at 99 ng/dL back in November so she had me up my daily dosage by 20%.
Two and a half months later my lab showed me at 37 ng/dL on the slightly higher dosage (perfect if you ask me).
My last lab in March had my level at 25 ng/dL (which seemed like a normal fluctuation from the 37 to me), and she had me drop the extra 20% of Spiro because she felt this was too low.
The Quest Diagnostic range for females is 2-45, so I can only assume she thought the lower level was somehow affecting my libido. 
I've been on the lower Spiro dosage for 6 weeks now (I'm assuming my level is probably back to around 99 again)  and my sex drive has not improved... much to the detriment of my relationship.
I think the only effect it's had on me is making my leg and facial hair grow a little bit faster again. :(

Now I've read where some doctors wait to prescribe progesterone until after 1-2 years of Estradiol, as it somehow may mark the end of breast growth. But, I have also met at least one girl that had both Estradiol and Progesterone prescribed right from the beginning of her HRT.
I know some of you are post-op so I assume you've been on HRT for several years.

I'm a 34-36 B bra size right now but my breasts are still tender, so I am assuming they're still growing.

Can I ask where you were in your transition when you added Prometrium?
I have been taking Spiro and Estradiol for almost 10 months now. I wan't to consider the possible unintended effects of taking Prometrium now, before I lobby my doctor for some (again).

Sorry for all the questions, but you girls seem to be very knowledgeable and experienced in this area, and I really appreciate your help here.
*** Any suggestions I make should never be used as a substitute for licensed medical advice ***
*** All of my personal pharmaceutical experiences I share, have been explicitly supervised by a licenced medical professional ***
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Laurie

 Hi  LexiDreamer

    I have been asking my doctor about adding progesterone to my regimen. I've only been on HRT for 5 months now. His last answer is that he wants me on a full dose of estradiol before prescribing it. I'm not sure at this point what he considers a full dose yet but I know I at the lower end of the "normal dose range". I guess I'll be interrogating him more on the 22nd for that information.

  Hugs,
   Laurie
April 13, 2019 switched to estradiol valerate
December 20, 2018    Referral sent to OHSU Dr Dugi  for vaginoplasty consult
December 10, 2018    Second Letter VA Psychiatric Practical nurse
November 15, 2018    First letter from VA therapist
May 11, 2018 I am Laurie Jeanette Wickwire
May   3, 2018 Submitted name change forms
Aug 26, 2017 another increase in estradiol
Jun  26, 2017 Last day in male attire That's full time I guess
May 20, 2017 doubled estradiol
May 18, 2017 started electrolysis
Dec   4, 2016 Started estradiol and spironolactone



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KayXo

I took Androcur within two months of starting HRT and this is a progestogen. I took progesterone 1 yr into my HRT for no specific reason other than just to see if it would make a difference.

The idea is to mimic young girls in puberty and wait to give progesterone but that's far as the rationale goes. No real science behind it.
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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LexiDreamer

Thank you Ladies!

My doctor sent the script in for Prometrium, but she doesn't think my insurance is going to cover it. Is there a generic I can suggest or should I really stick with the brand name version?
*** Any suggestions I make should never be used as a substitute for licensed medical advice ***
*** All of my personal pharmaceutical experiences I share, have been explicitly supervised by a licenced medical professional ***
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AshleyP

Quote from: LexiDreamer on May 05, 2017, 11:11:27 AM
Thank you Ladies!

My doctor sent the script in for Prometrium, but she doesn't think my insurance is going to cover it. Is there a generic I can suggest or should I really stick with the brand name version?

Yes, there is a generic, but it's still pretty expensive. Kay once suggested to me that I ask a compounding pharmacy, and it cheaper there. The two I talked to have some weird dosage rules that they can't compound a med if it's a standard dosage, i.e. 100mg or 200mg. I don't know if I understood them right though. They didn't really want to talk to me when they discovered I didn't already have a prescription.

All the best,
--AshleyP
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KayXo

Maybe your insurance will cover it if you mention you can't tolerate the progestin, medroxyprogesterone acetate (i.e. depression). It worked for me. I get it for free. :)

Apparently, Prometrium is just as expensive as the generic. No difference, is what Merck claims.
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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LexiDreamer

My insurance covered it. They gave me generic though. Round pink balls. They look strange for meds.
I started it tonight as the instructions say to take it once a night.

Anything I should watch out for?

Sent from my SAMSUNG-SM-N910A using Tapatalk
*** Any suggestions I make should never be used as a substitute for licensed medical advice ***
*** All of my personal pharmaceutical experiences I share, have been explicitly supervised by a licenced medical professional ***
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ainsley

Some people say I'm apathetic, but I don't care.

Wonder Twin Powers Activate!
Shape of A GIRL!
  •  

LexiDreamer

*** Any suggestions I make should never be used as a substitute for licensed medical advice ***
*** All of my personal pharmaceutical experiences I share, have been explicitly supervised by a licenced medical professional ***
  •  

AshleyP

Quote from: ainsley on May 06, 2017, 11:29:32 PM
Vivid dreams. :)

Funny that you'd mention that. While I'm not taking progesterone, it seems that my dreams have been much more vivid since beginning HT. As a practiced lucid dreamer, I've also found it much harder to "enter" my dreams, too.

All the best,
--AshleyP
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ainsley

I could not believe the vivid dreaming I began to do when I started progesterone.  They are unlike anything I have dreamt before taking it.  I still dream very vividly, and they seem so real!  Also, I remember them--another thing I never used to do.

It's crazy, but I like it, tbh.   :eusa_dance:
Some people say I'm apathetic, but I don't care.

Wonder Twin Powers Activate!
Shape of A GIRL!
  •  

LexiDreamer

I'm already a dreamer... hence my username. ;)

But the Prometrium has definitely amplified my dreaming! And yes, my dream recollection seems to be sharper too.

I've only taken it for 3 nights and overall I'm feeling pretty good. My mood was very calm and upbeat this weekend.

Hopefully it won't be long for the libido lifting effects to kick in. :)

Thank you so much for the recommendation!
*** Any suggestions I make should never be used as a substitute for licensed medical advice ***
*** All of my personal pharmaceutical experiences I share, have been explicitly supervised by a licenced medical professional ***
  •  

ainsley

Quote from: LexiDreamer on May 08, 2017, 09:41:28 AM
I'm already a dreamer... hence my username. ;)

But the Prometrium has definitely amplified my dreaming! And yes, my dream recollection seems to be sharper too.

I've only taken it for 3 nights and overall I'm feeling pretty good. My mood was very calm and upbeat this weekend.

Hopefully it won't be long for the libido lifting effects to kick in. :)

Thank you so much for the recommendation!

So glad to hear you are seeing good results thus far from it! 
Keep us posted.   :eusa_dance:
Some people say I'm apathetic, but I don't care.

Wonder Twin Powers Activate!
Shape of A GIRL!
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