Can you take progesterone sublingually?

[Angélique LaCava]

I'm on medroxyprogesterone, yea ik not good for you and I don't want to hear a lecture about that, just want to know if I can take it sublingually to increase my progesterone levels.

[Wednesday]

yea ik not good for you and I don't want to hear a lecture about that

[Spunky Brewster]

No, take it with water and milk and with food. It probably increases bio availability by twofold, if its anything like other progestins.

[Harley Quinn]

No, just take it with food. It's just like taking Spiro. Food increases the dose that stays in your system.

[bubbles21]

Why is it bad? When i took it i just took it with water normally after i ate, but sometimes just with water. I just took my spiro and progesterone in the same sitting.

[V M]

I tried taking progesterone sublingually once, tasted nasty and made me sick 

[TonyaW]

No, just take it with food. It's just like taking Spiro. Food increases the dose that stays in your system.

There would be no advantage to taking it sublingually.  The first pass liver metabolism is not an issue like it can be for the estradiol.  Take with food as Harley says.

Why is it bad? When i took it i just took it with water normally after i ate, but sometimes just with water. I just took my spiro and progesterone in the same sitting.

It's not necessarily bad but some have some problems with it (if I'm remembering  it right, look up Harley Quinn's posts for one).

The micronized form of progesterone  [Prometrium] is generally less problematic but also more expensive so usually will start with the medroxyprogesterone as most can tolerate it




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[rose]

I heard it have androgenic affect ( increase body hair , increase  libido etc )


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[KayXo]

The oral bioavailabilty of Medroxyprogesterone acetate is close to 100% (in contrast to about 5% for bio-identical progesterone) so there is no point of taking it sublingually. Food or no food makes no difference.