Anti rejection drugs are nasty in that you are subject to every bug that comes your way and they can cause undesirable physical changes so they are best avoided if possible.
As for yeast infections, they are not much of a problem as we develop natural vaginal bacteria. As long as the natural protective bacteria exist, there really isn't an odor or much upkeep other than dilation. If you douche often, that can result in infections as it eliminates the protective bacteria. Self lubrication depends some what on the type of surgery you have but the tissue can convert to vaginal tissue and remain moist. For most of the surgeries, lubrication before sex is desirable.
In discussing sexual response, you need to remember that some women are frigid. Should this happen to you, there are treatments that help this problem including low dose testosterone. A woman's orgasm is not like a male orgasm in that it's more difficult to have and it's a full body experience as opposed to being located in the lower regions. If sex is to be successful, your partner will have to prepare you properly before sex so any partner you select should care as much about your pleasure as theirs.