I had to stop estradiol about 3 weeks ago, until I can stop smoking, I went for a blood test 2 days ago and my levels are 10 points higher than when I was taking the estradiol. I just wanted to know if I am not taking the estradiol, and my levels are high still, am I still at risk for heart attack and/or stroke? I would ask my doctor but he wont be back until late February. the only thing that I have been taking is phyoto estrogen creams and spironolactone. I am just worried cause I don't want to be at a higher risk. I already cut my smoking in half, and I am on my way to fully quitting, Just strange that it is higher than it was when I was on the medication. Thank you for any info you can give. Thing is I thought I was still seeing changes in my body, but just thought it was in my head. now that the levels are so high I must be getting changes. My testosterone levels have always been extremely low, when I was 1st tested my doctor told me I have the testosterone of a woman to begin with.