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Hormones

Started by Marina1993, February 22, 2018, 07:54:56 AM

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Marina1993

I'm a 25 year old intersex woman. Born with partial androgen insensitivity. My genitals were more male than female so i was raised male. I changed my gender when I was 16. Still have testicles. Started hormone treatment at 19. Treatment was almost the same as for a transgender woman. Estrogen(pills) and an antiandrogen(Androcur).

6 months ago I quit the anti androgen and use estrogen(patches) only since then. The testosterone kept being stable (between 0.7-1.3 nmol/l) in female range for 5 months, Estrogen levels became a little too high and my gynaecologist lowered the estrogen dose.

The estrogen got down to a lower and better level and is now 240pmol/l but after 2 months of the lower dose estrogen and 6 months without antiandrogen testosterone level is now 4.1 nmol/l. Normal range for female is 0,3-3.0 nmol/l as far as I know.

I'm wondering how it can be elevated like that when it was 1.3nmol/l last month after 5 months without antiandrogens. I thought after 5 years of anti androgens and 5 months of being stable without antiandrogen it wouldn't really change again.

Before I started hormone treatment my testosterone level was 12 nmol/l but because of my partial insensitivity to androgens I didn't get into male puberty. Because an orchidectomy isn't possible for now I still have my testicles.

Even though partial insensitivity to androgens Is there any possibility of defeminization and masculinization of the body with a testosterone level of 4.1 nmol/l? If not, at what testosterone level it possibly will?

Would it be better to wait another month and see if it stabilizes, or would it be best to up the dose of estrogen to block the testosterone better,
or taking an anti androgen again?(Which I don't prefer because of the possible long term side effects)
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Jessica

Hi Marina 🙋‍♀️ Welcome to Susan's Place!  I'm Jessica.  I won't try to answer your question, I'm still learning how to keep my levels stable. 
I'm embarrassed to say that you have been missed being properly welcomed here a Susan's for quite a while, so I'll post some links that may help you get better acquainted with the site even though you may have already found them.  Again, welcome to Susan's Place!  I glad your here!

Please feel free to stop by the introductions forum
https://www.susans.org/forums/index.php/board,8.0.html to tell the members about yourself. 

Things that you should read



"If you go out looking for friends, you are going to find they are very scarce.  If you go out to be a friend, you'll find them everywhere."


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mm

Marina1993, best to work with your drs as they are the ones who should know how to adjust your hormone input to get the result you need and want.
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Myranda

Marina,  I wouldn't worry about it too much, but I would definitely talk to your doctor about it as wel las keep on eye on your T levels over time.


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KayXo

As you are partially insensitive to androgens, I'd think that a level slightly above female range wouldn't cause much problems. Also, your reduction in estrogen dose could account for the rise in T as estrogen lowers production of T.

I'm not an expert, however and you should discuss this with your doctor.
I am not a medical doctor, nor a scientist - opinions expressed by me on the subject of HRT are merely based on my own review of some of the scientific literature over the last decade or so, on anecdotal evidence from women in various discussion forums that I have come across, and my personal experience

On HRT since early 2004
Post-op since late 2005
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PurplePelican

Quote from: KayXo on February 22, 2018, 12:08:56 PM
As you are partially insensitive to androgens, I'd think that a level slightly above female range wouldn't cause much problems. Also, your reduction in estrogen dose could account for the rise in T as estrogen lowers production of T.

I'm not an expert, however and you should discuss this with your doctor.

This would be my guess as well.
This is not medical advice. Always consult your doctor.
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