Quote from: KathyLauren on April 05, 2018, 11:52:37 AM
Maybe check with your HRT doctor and/or Dr. Brassard whether you can stay on blockers right up to surgery. The risk factor they are trying to mitigate is that estrogen increases your risk of blood clots.
It's been stated in a very recent study that transdermal estradiol does not increase the risk of blood clots so you can share this study with Dr. Brassard, if you wish. Also, one should question why ciswomen who produce estrogen are allowed to continue producing estrogen while undergoing surgery while we are denied the same hormone if taken non-orally. This should be discussed with the surgeon. Finally, it's been admitted recently in a study that there is actually no evidence supporting this approach. I would urge you to go and visit the transhealth section of the University of California San Francisco where they discuss this more in detail and state that first, there has been no study of the risk of thromboembolism with the use of bio-identical estradiol during, before and after surgery and that, second, there is no actual evidence to show that transwomen should cease estrogen prior to surgery if risk factors are absent.
Also, certain anti-androgens and other hormones have been found to not affect the development of clots such as bicalutamide, LhRh agonists, progesterone and finasteride/dutasteride so if you are taking any of these, you should ask the surgeon why you need to stop them. As far as spironolactone goes, some doctors insist it must be stopped due to its effect on electrolytes and as the above poster shows, it would be wise to follow their recommendations.

Be smart, stay safe and talk with your surgeon if you have any concerns.
Quote from: Stella92 on April 07, 2018, 02:17:34 AM
To add to that, when we take the E in pill form we have actually a slightly higher risk of blood clots then cis women. But that's the same for cis women on birth control medication.
The risk with birth control pills according to some studies would appear to be greater than on oral bio-identical estradiol, especially considering the doses we typically take them at.
QuoteDue to that, in the Netherlands, its no longer required to stop the HRT prior to the GCS, as their not asking cis women to stop their birth control prior to any surgery and the increased risks seems minimal.
That is indeed strange that if birth control pills can be continued, transwomen are denied estradiol before surgery, which is a lower risk.

Quote from: Paige on April 08, 2018, 09:29:35 AM
Birth control pills aren't a good comparison because they usually aren't just estrogen.
Birth control pills contain ethinyl estradiol as opposed to bio-identical estradiol which we take. Ethinyl estradiol (EE) has a far greater impact on the liver and coagulation. Some progestins contained in birth control pills may apparently further increase the risk of clots.
Quotevaginal estrogen doesn't raise the risk at all.
It seems to me, based on all the studies I've come across, that when bio-identical estradiol is taken non-orally, the risk of clots/thromboembolism is negligible, even in individuals at greater risk. As always, verify with your doctor, follow their recommendations and do your own research, if you wish.