I've received quite a few comments on my eyelashes - not from photos (difficult to tell that way) but in-person. I started applying Latisse in early 2017.
Latisse requires a prescription in several countries including the US. I think the requirement is due to potential side effects that are disclosed with a prescription. Some Latisse users have found their eyelids turn slightly purple (free eye shadow!) and a subset of those have reported discoloring below the eyes which wouldn't be as attractive. In few rare cases, Latisse has been known to permanently darken the iris - turning blue or hazel/green eyes to brown. My eyes are hazel so I was very concerned about the iris color issue.
A year+ later I've applied Latisse once per day and haven't noticed any side effects. The instructions are clear: avoid dribbling any Latisse in your eyes, apply only to upper eyelashes at the lash line, and don't apply it to lower eyelashes. They also say don't re-use the applicator brushes to help avoid contamination. One thing that discouraged me from over-applying is it's expensive... retail price is $120 US dollars for a tiny 3ml container. I was able to find a discount supplier in Pennsylvania (I live in Seattle) - a doctor writing prescriptions based on a questionnaire, uploaded photos of your eyes and photo ID. I know that sounds a bit sketchy but the main thing is I wanted a domestic not overseas source, and not a generic Bimatoprost which might have higher risk of counterfeiting.
I found the one month supply lasts 3 months if I'm careful. I buy the 5ml size now, still pretty small but I've found each 5ml lasts almost a half year. The main thing is I tossed the applicator brushes supplied with Latisse - those are huge and almost seem designed to waste the stuff. Even worse, I found the included brushes difficult to use without smearing Latisse into my eyes. I quickly tossed those and bought a set of 100 eyeliner brushes on
Amazon for $8.
6 inch / 15cm boxI keep the overpriced little bottle, toss everything elseDisposable eyelash brushes from Amazon (right side) are better qualityEvery time I open a new package of Latisse I feel guilty about the environmentally wasteful packaging. Inside this pretty big box is a bunch of stuff I immediately discard leaving a tiny little bottle. The bottle would be even smaller if you toss the green cover which fits over the screw cap but I discovered a problem: don't do that. If you toss the green cap on the bottle, the remaining screw-cap portion can be over-tightened and a crack forms so it all spills out. Expensive mistake.
I don't know if the instructions to limit application to upper eyelashes is to reduce side effects, but I think an additional reason is: this stuff made my upper eyelashes grow really well, and directly applying to lower eyelashes might cause those to grow too long and look weird. I had to carefully trim two individual upper eyelash hairs with small scissors - shows just how well this stuff works.
For the first month I didn't notice any effect at all. Nuthin'. Two or 3 months, wasn't sure - maybe a bit fuller. At month 4, wow. I was always a Fail at applying false eyelashes (they stuck just fine to my fingers or cheeks, but nowhere else) and after Latisse I haven't had any need to try false lashes again. Even better, I almost never apply mascara now - they're quite visible without it.
I didn't take close-up before photos, but my results are similar to the ones shown on Latisse and related web sites. My understanding is if I stop, my eyelashes will look good for a few weeks but will return to their previous condition after 4 months following the regular hair growth cycle.
So with a word of caution to know in advance about the side effects, after more than a year I've found this has worked great.