This is just my take and without knowing the details, but If you're out at work, I'd do the following:
Advertise and run a seminar internally on non-binary/trans gender identities. Keep it positive, informational and reference good sources. - I've done this several times with my employer.
People fear and hence ridicule what they don't know or understand. Give them the knowledge to help them understand and become an ally.
If after that you still have trouble, then you know these are not people you want in your life. X
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