Some thoughts:
1. You really neeed to talk to your doctor about trying injections instead of pills. With the pills, the E has to be processed through your digestive system and liver. With intramuscular injection, the pure stuff goes right into your bloodstream.
2. You need to talk to your doctor about your blood estradiol levels. YMMV, but in order to stop depression and get good feminization, I need to be at some pretty high levels of E and it's a constant battle with the doctors to keep my levels up.
3. Have you tried progesterone for breast growth?