Hormone gone out of production

[Dany]

Hi!

The hormone I was taking up until today has gone out of production after having been super hard to find it in pharmacies for like a month. I used to take Estradiol, brand named Estrell here by biolab. So now I'd like to know your opinion: having in mind the fact that I've always taken my hormone orally, what are the advantages of taking it  via injection? Will there be any improvements in my HRT as a whole, which has been spotless till now, or maybe no difference? There can't be any complications, can there?

I can only imagine how hard it'll be to not take my hormone for two weeks until I can consult with the doc and get it all sorted. I've never spent longer than a day without my sweet, sweet drug. That's a drag.

Thanks a million for your input.

[jill610]

Hi!

The hormone I was taking up until today has gone out of production after having been super hard to find it in pharmacies for like a month. I used to take Estradiol, brand named Estrell here by biolab. So now I'd like to know your opinion: having in mind the fact that I've always taken my hormone orally, what are the advantages of taking it  via injection? Will there be any improvements in my HRT as a whole, which has been spotless till now, or maybe no difference? There can't be any complications, can there?

I can only imagine how hard it'll be to not take my hormone for two weeks until I can consult with the doc and get it all sorted. I've never spent longer than a day without my sweet, sweet drug. That's a drag.

Thanks a million for your input.

The only real advantage I am aware of to taking it as injection is convenience and a potentially reduced load on the liver and kidneys. You will experience more mood swings on injections.

[GordonG]

You will experience more mood swings on injections.

That is not true from what I have read. Many people inject less E but more frequently and that can eliminate mood swings.

[Dany]

Yeah...I guess  adjusting that is the easy part. I'm more worried about the next two weeks being completely starved of E.

[jill610]

That is not true from what I have read. Many people inject less E but more frequently and that can eliminate mood swings.

Speaking from experience, it is true unless you inject daily. There is a massive peak when you inject and an equally large trough right before you inject. The only thing you can really do is mitigate by reducing the peaks and troughs by increasing frequency.

I inject weekly because biweekly cause huge swings, and live on imitrex the last two days of the cycle.

[jill610]

Yeah...I guess  adjusting that is the easy part. I'm more worried about the next two weeks being completely starved of E.

You'll be fine. Two weeks is not that big of a deal. Had to go off for a month+ prior to gcs and it's a little annoying but not the end of the world.

[Dany]

You'll be fine. Two weeks is not that big of a deal. Had to go off for a month+ prior to gcs and it's a little annoying but not the end of the world.

Except going off E for the surgery is a different thing. Not that it isn't complicated but uh, you're about to achieve the most important part of both your HRT and of your life there. Here I'm just sorting out a problem. So annoying.

[jill610]

Except going off E for the surgery is a different thing. Not that it isn't complicated but uh, you're about to achieve the most important part of both your HRT and of your life there. Here I'm just sorting out a problem. So annoying.

It's actually exactly the same thing. Just because there is a surgery at the end of it doesn't make the effects any different or easier.

[Dany]

It's actually exactly the same thing. Just because there is a surgery at the end of it doesn't make the effects any different or easier.

Yeah? I thought having in mind your organ of terror is meeting its doom would make that easier, apparently I was wrong.

[GordonG]

Speaking from experience, it is true unless you inject daily. There is a massive peak when you inject and an equally large trough right before you inject. The only thing you can really do is mitigate by reducing the peaks and troughs by increasing frequency.

I inject weekly because biweekly cause huge swings, and live on imitrex the last two days of the cycle.

I wasn't trying to undermine your experience. I read your post as a blanket statement. My bad! Yes, the closer together the injections, the less the swings. I did a lot of reading on this. I guess it's a YMMV thing also.

[Rachel]

I have taken oral and injectable IM and subQ. I think subQ is absolutely the best. I do feel an up and down in the cycle but by far I feel the most level out of the HRT I have taken.

[Dany]

I'll talk to the doc, let's see what he says. But I'm definitely going for injectable.