What Makes a Man

[Natasha]

What Makes a Man

http://aebrain.blogspot.com/2008/10/what-makes-man.html
10/16/2008

Or rather, what makes someone genetically male?

Our results reveal potentially important SRY regulatory elements,
mutations in which might underlie cases of idiopathic human XY sex
reversal.

That's from New insights into SRY regulation through identification of
5' conserved sequences http://www.biomedcentral.com/content/pdf/1471-2199-9-85.pdf by Ross D.F.G, JBowles J., Koopman P., and Lehnert S. in BMC Molecular Biology 2008, 9:85 (14 October 2008).

The problem is that XY sex reversal happens a lot, and we're not sure
why. Many women are born apparently "genetically male", with 46XY
chromosomes. But actually genetically female.