It depends on the person and what your bone structure is to begin with.
Losing weight is always good.
Do not be surprised at how things change.
I'm going to include a picture here of me after 3 months of spiro (and nothing else), then me one entire year later. Look at how the face becomes more delicate and especially all the stuff in the lower part of the face and neck thins out.
Also included here is a picture from last summer with about three months of ESTROGEN added to the spiro. Note how the cheeks do flesh out.
I was 39 in two of these pics. Younger people tend to do better.
Like others have said, you can use tricks too. How you do your makeup can make a big difference in what parts of your face are accentuated. Minimize the masculine stuff; maximize feminine aspects. Even your haircut changes the shape of your face, you can use it to frame your face, or cover up a square jaw, or whatever else.
I usually thought out my appearance pretty well, to help shape my face. For me, I was passing 95% of the time at the time when the bottom picture was taken.
