About two years ago I took on my own a course of Estradiol, about two weeks, and what I found apart from lots of positive effects on my state of mind, was an unexpected series of improvements on my health. It eliminated almost completely a persistent rhinitis, back pain, pain on the shoulder, it enhanced concentration and endless benefits came along. This is something I'm investigating now with my GP (I've been today to him, has been a bit difficult to start the conversation, but he's such a nice and professional guy). I'm not ready to make a transition but I'd take about a third/quarter of the usual transition dose of Estrogens just to alleviate my health issues and improve my mood. It helps me a lot, a lot, and this might lead me further down somewhere, but I'm ok with who I am, I'm just trying to be healthy.
BTW... any people here from London up for meeting?