I think that the bottom line is that we are all human, and at some point in our lives we have always experienced regret over something that we have done or failed to do. Some of these are career choices, lovers, wives and husbands, other relationships, converting to or joining a religion, clubs and associations, investments and other financial issues, and no doubt many more. Even some of these can have such a dramatic effect on our lives that they too can lead to suicide or other harmful actions.
One issue that is hard to cope with is that our minds are so complicated that once a seed has been planted, and it is nurtured so that it grows strong and healthy, the final result is often not realized until it blooms, and by then it is too late. Humans are great at convincing themselves over issues like this. Some are so convincing that professionals are even fooled by the seemingly rational being before them. There aren't many safe guards out there and it's too bad that the one that we do have are seen by some as "barriers set up by gatekeepers" but heck what else is there. How often have we heard "I should know what's best for me", "Who knows me better that me", "I'm an adult and I know what's best" etc. We see it all the time, heck I was even one of those.
Therapy, letters and HRT is one thing, but I truly believe that the best safe guard that we have is the "Real Life Test or Experience". I firmly believe that TS should be required to live one full year not only in their gender but in all aspects of life from relationships to employment as what the heck do you have to loose. Granted even then there may be those who still suffer regrets after SRS but I believe that the safe guards in place now do work.
Steph