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Why the Y chromosome can trigger sex disorders

Started by Natasha, September 24, 2009, 04:52:55 PM

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Natasha

September 24, 2009, 04:52:55 PM
Why the Y chromosome can trigger sex disorders

http://ec.europa.eu/research/headlines/news/article_09_09_24_en.html
9/24/09

Research on the mystery behind the Y chromosome's role in sex disorders kicked off a few years ago, when the David Page lab at the US-based Whitehead Institute for Biomedical Research reported the discovery of eight large areas of palindromes, or mirror-imaged genetic sequences, along the Y chromosome.

This sex chromosome, the researchers had reported, cannot swap genes with another chromosome because it has no partner. Gene swapping helps secure good genes, and the problem with the Y chromosome is that it can only exchange genes with itself, so palindromes play a major role in this process. The Y chromosome folds itself in the middle of palindromic regions, effectively pairing identical sequences in order to make the most of a good genetic swap.
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