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Engineered Rabbit Penises Raise Human Hopes

Started by Miniar, November 09, 2009, 02:50:58 PM

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Miniar

Using tissue grown in a laboratory, researchers have engineered fully functional replacement penises. The organs were made for rabbits, but the technique may someday be useful for people.

"This technology has considerable potential for patients requiring penile construction," wrote researchers in a study published Monday in the Proceedings of the National Academy of Sciences.

Leading the team was Anthony Atala, director of Wake Forest University's Institute of Regenerative Medicine. Atala is best known for developing a technique in which cells are taken from an organ and sprayed onto a frame made of collagen, the primary structural protein in animal tissue. The structure is then bathed with growth-stimulating compounds and kept in an oven that duplicates the body's temperature and chemical composition.

Given these starting conditions, natural biology does the rest. The cells divide and arrange themselves in natural, working configurations.
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Link; http://www.wired.com/wiredscience/2009/11/penis-engineering/
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A friend linked me this.
I'm still... out of words



"Everyone who has ever built anywhere a new heaven first found the power thereto in his own hell" - Nietzsche
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Lachlann

Don't be scared to fly alone, find a path that is your own
Love will open every door it's in your hands, the world is yours
Don't hold back and always know, all the answers will unfold
What are you waiting for, spread your wings and soar
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Tammy Hope

I wonder if that woiuldn't eventually lead to true gender reconstruction.

i.e. eventually you could create functioning testes, ovaries, and so forth...
Disclaimer: due to serious injury, most of my posts are made via Dragon Dictation which sometimes butchers grammar and mis-hears my words. I'm also too lazy to closely proof-read which means some of my comments will seem strange.


http://eachvoicepub.com/PaintedPonies.php
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Miniar

I've googled it three times already trying to make sure it's not a gag.



"Everyone who has ever built anywhere a new heaven first found the power thereto in his own hell" - Nietzsche
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Lachlann

Quote from: Laura Hope on November 09, 2009, 02:59:34 PM
I wonder if that woiuldn't eventually lead to true gender reconstruction.

i.e. eventually you could create functioning testes, ovaries, and so forth...
Well they've been dabbling a lot with this technology, so they might experiment.

It's exciting and kind of frightening at the same time.
Don't be scared to fly alone, find a path that is your own
Love will open every door it's in your hands, the world is yours
Don't hold back and always know, all the answers will unfold
What are you waiting for, spread your wings and soar
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Kurzar

That and is it something anyone will be able to even afford? In my lifetime?
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Miniar

Quote from: Kurzar on November 09, 2009, 03:51:55 PM
That and is it something anyone will be able to even afford? In my lifetime?

Maybe if we start saving up... oh.. now?



"Everyone who has ever built anywhere a new heaven first found the power thereto in his own hell" - Nietzsche
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Lachlann

Quote from: Kurzar on November 09, 2009, 03:51:55 PM
That and is it something anyone will be able to even afford? In my lifetime?

Probably. While current bottom surgery isn't cheap, overtime I can see this being just as available. They're working on this type of technology for the benefit of everyone, not just the rich guys.
Don't be scared to fly alone, find a path that is your own
Love will open every door it's in your hands, the world is yours
Don't hold back and always know, all the answers will unfold
What are you waiting for, spread your wings and soar
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Catherine

My first thought when I read this was.... I wonder when the proceedure is fit for humans will it make the humans act like rabbbits ??? :D :D
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Kurzar

Quote from: Catherine on November 09, 2009, 04:16:42 PM
My first thought when I read this was.... I wonder when the proceedure is fit for humans will it make the humans act like rabbbits ??? :D :D

My sex drive is insane anyways lol   Unfortunately there is no 'saving up' for me. I am already in debt over $120,000 in medical bills and that isn't counting any other bills like our $60,000 something mortgage. *sigh*
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Keroppi

Quote from: Laura Hope on November 09, 2009, 02:59:34 PM
I wonder if that woiuldn't eventually lead to true gender reconstruction.

i.e. eventually you could create functioning testes, ovaries, and so forth...
I'm sure the day will come when any specific organs can be created. But creating it is one thing, successfully transplanting it is quite another...
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deviousxen

My hopes are for this technology to be utilized in tissue grafting in the neovagina.

Basically start with SRS, and then go in for treatments/injections/grafts to make the tissue more and more natural. Implant things that should be there, etc...


If they can do this... With rabbits. Then why the hell not?
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metal angel

i was about to post this but i see someone beat me to it
http://www.abc.net.au/news/stories/2009/11/10/2738398.htm

I think it's true, they already do some stuff a bit like this for growing skin for burns victims and i think maybe also bone, how they'd build the scaffold might be a bit of an expense/logistics issue though, a penis is a pretty complicated organ compared to a layer of skin.

I think there'd be a moderately high risk of tissue grown this way turning cancerous, so it may be a long while before they are willing to graft it onto a human without some immediate and direct threat to their life (burns, heart failure, some other vital organ not working). But being somatic cells (normal cells) rather than stem cells probably makes it a bit safer. Also not having to find ova or embryos for stem cells makes it likely to be cheaper and easier to obtain. I think it will take at least 5 years though (probably a lot longer) to get to human stage.

One thing that i'd be particularly sceptical of is that they don't seem to be saying much about nerve tissue, i'd say that was pretty important for a sex organ, but given the quality of current phaloplasty it's gotta be an improvement on that, and won't literally cost an arm. Even if i'd been more tempted before, the donor-site photos i've seen for phalo are enough to turn me right off it.
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Allamakee

The research is due to be published in the Proceedings of the National Academy of Sciences, but the article doesn't seem to be online....yet.

However, Dr. Atala has been working on this project for 18 years, which prompted me to check for prior research.  Here is an abstract from seven years ago, where he reported success with constructing penile erectile tissue in rabbits.
http://www.ncbi.nlm.nih.gov/pubmed/12352353?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5

A possible problem with the current technique is that it relies on multiplying erectile cells taken from the patient:
QuoteIf the scientists do try and help people with this research, naturally they will not use rabbit cells with men.

"We would take a small sample of a patient's erectile tissue, extract the cells we need and multiply them in the laboratory," Atala explained. "The resulting tissue would be a perfect match for the patient.
http://www.livescience.com/health/091109-artificial-penis-tissue-rabbits.html

I'm not sure that that donor erectile cells could be used, but if so I don't think potential donors would be hard to find.  All it would take is a post here.  :D
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The None Blonde

Amazing news for f2ms :) I'm really happy to finally see things progressing for you guys.... Its about time :)
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metal angel

actually females (at least biofemales) have plenty of erectile tissue, it's just a different shape and differently shaped. I have heard though that the total volume is comperable to a male, and i heard that from an anatomy professor. So there's donor tissue available on an FtM, not much to spare and it's in obviously sensitive bits but you wouldn't need to resort to a non-patient donor.
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Miniar

... hubby has looked at this and gone "hrrrmpfh!.. this means you could, in theory, when the technology is ready, choose your own size! that's not entirely fair... I didn't get to choose... " ^^



"Everyone who has ever built anywhere a new heaven first found the power thereto in his own hell" - Nietzsche
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deviousxen

Quote from: The None Blonde on November 10, 2009, 06:48:43 AM
Amazing news for f2ms :) I'm really happy to finally see things progressing for you guys.... Its about time :)

Its amazing news for anyone with flesh bodies. This science could be applied to anything else assuming one had a different approach for vaginal stuff...


But seriously... I agree.
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The None Blonde

to be honest, im more pleased for f2ms to see some decent surgical result in the near future.... We have a fairly good result, and while its not perfect... i'd rather that than a penis... f2ms have had hard luck (pardon the pun) till now... this is a glimmer of light that things can be better, so without diverting thier spotlight, fair play, and i hope this does become available.
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Allamakee

Quote from: metal angel on November 10, 2009, 07:04:40 AM
actually females (at least biofemales) have plenty of erectile tissue, it's just a different shape and differently shaped.
Great!  That is welcome news.

I still can't find the article or abstract online at Proceedings of the National Academy of Sciences .  However, Wake Forest did publish a press release.
http://www.wfubmc.edu/penile-erectile-tissue-replacement.htm
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