Hey Andrew, welcome!

I'm not sure if this is what you meant by your question, but I was in a relationship with a bio guy for around six months. We were friends before we were together, so he knew from the get go that I was a guy. I thought he wouldn't accept me as male, but after telling him about my situation he started calling me 'bro' and joking about it, like it wasn't that big a deal. He later revealed to me that he was bi, and had been interested in my for a while but couldn't get up the courage to talk to me about it. He said my being male didn't change anything for him.
We were 'guy pals' as some people might put it, so we talked about sex and porn and all of those kinds of things (while I constantly tried to get him to admit he was totally into that guy

) so I had openly explained to him that I couldn't stand the idea of being in a submissive role in a relationship, and that just because I was born 'female' didn't mean it was okay for everyone to assume I'd love to sub. -shudders-
So when we became an item he really allowed me to take the lead, which was awesome

We're over now, but it was pretty good while it lasted. He never seemed challenged by my masculinity, and having to take a more submissive role in the relationship really didn't bother him. But every person is different.
As to other men in my life, well I can't say as I've really had any overly bad or overly good reactions. Everyone just sort of went 'Oh, okay...if you think that's what's right for you', and everything went on as normal. I have never been 'one of the guys', my whole life my friends have been almost constantly female only. That's changed a lot in the last few months, and I now have about even numbers between my female friends and male friends, but I don't think that really matters.
If you're a little girly in the things you do, it doesn't mean you're any less of a guy. I wore thick black eyeliner to work today for the hell of it, and everyone was like 'You look rockin''! I think it's more important to be true to yourself, than to worry about whether you're doing everything in a 'masculine' way or not.

Wow, I've rambled on! Okay, stopping now!