Oddly enough, I didn't receive any looks or comments when I started my transition/HRT back in the midwest a year ago. I seen the same 3 pharmies every month and they were nothing but smiles or at least professional and courteous. One of them even hugged me on my last visit with them, which was just after Xmas - if it wasn't for the fact that she used my chosen name, I would have thought she was mistaken me for some other lady.
After moving several months ago, two young guys (perhaps in training or just new) helped me at the pharma counter on my first visit there. They were nice and seemingly professional, but they seemed just a little curious about or interested in me... I even thought for a moment or two that I was going to hear either a pick up line or a comment about my combination of scrips - but nope. They remained professional, while I didn't know whether to be flattered or worried about being clocked.
Having gone back a few times now, they are still nice and I've been without incident. Fortunately.