Hi,Jerica
I'm a newbie so I just noticed this post. I was recommended by my Dr to administer in the thigh muscle (largest) or the bicep muscle. The reason being, is there is more fat deposits in your rear and some of the fat may absorb the Estradiol making it not as effective. just some FYI
I have been on IM for about 6-months now, every two weeks. I have just gotten use to giving myself injections, but still a bit nervous at times.
I have never been one to fear shots, but that first one I gave my self must of took 45 minutes. I tried 4-5 times to poke my leg but my reflexes stopped me.

Mine is in caster oil, it literally takes 7 minutes to fill the syringe, and then you have to inject slowly. Oh and YES don't hit a bone

Shelly