Quote from: Natasha on June 21, 2013, 12:06:51 AM
The big question then is; how does a man feel female intrinsically despite having genitalia and a body? What's the biology behind it?
Very controversial topic.
If we're talking about a biological predisposition... current research is pointing towards the effects and timing of hormones during prenatal development.
I'm not qualified to talk at length on the subject, but what follows is an abstract representing the direction some of this research is taking.
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Sexual hormones and the brain: an essential alliance for sexual identity and sexual orientation.
Garcia-Falgueras A, Swaab DF.
Source
Netherlands Institute for Neuroscience, Amsterdam, The Netherlands.
Abstract
The fetal brain develops during the intrauterine period in the male direction through a direct action of testosterone on the developing nerve cells, or in the female direction through the absence of this hormone surge. In this way, our gender identity (the conviction of belonging to the male or female gender) and sexual orientation are programmed or organized into our brain structures when we are still in the womb. However, since sexual differentiation of the genitals takes place in the first two months of pregnancy and sexual differentiation of the brain starts in the second half of pregnancy, these two processes can be influenced independently, which may result in extreme cases in trans-sexuality. This also means that in the event of ambiguous sex at birth, the degree of masculinization of the genitals may not reflect the degree of masculinization of the brain. There is no indication that social environment after birth has an effect on gender identity or sexual orientation.
Copyright 2010 S. Karger AG, Basel.
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All that being said... biology is not destiny. It is still possible to be socialized as male, female, someplace in between... or to remain largely unsocialized as either gender.
If there is any 'disorder' related to being transgender, it doesn't involve biology. The biology simply represents a natural variation in prenatal development. The 'disorder' is a result of the conflict between biology, socialization and social acceptance. If sex, gender, sexual attraction, socialization and gender role all match up to what society expects... congratulations! You've won a free pass in the gender binary grand prix.
If any part of this mix is in conflict then you are more susceptible to personality disorders that may develop from destructive socialization and conditioning, i.e. social isolation, shame, fear of violence, fear of losing family/tribe, loss of authenticity, emotional distance, and generally just trying to conform to an ideal that is not genuinely "you". Billions of people have the same sense of male or female gender identity as you do and they suffer no ill effects. Your gender identity is normal. It just happens to be in conflict with other aspects of your body and societal biases.
Soooo.... the obvious follow-up question is... if there is a biological basis, can it be cured?
...I'd say, lets not go there.
Although there is some interesting research in gene therapy and gene triggers, making changes in utero would be unethical and making changes after someone reaches the age of consent probably would not alleviate any issues compounded by socialization. (If we are talking theoretically, we should also be able to isolate the brain chemistry that predisposes individuals to be anti-lgbt legislators. Let's find a cure for that before tinkering with the biology for gender identity.)
Sorry for the length and dryness of the post. I know not everyone appreciates this and would prefer a more spiritual explanation. If you are interested in additional research that is being done, google "aebrain gender identity" or "brain gender identity", (and ignore any links to studies that are more than 10 years old.)