The P creams are usually Progesterone derived from soy. Usually applied on the insides of the upper legs or the undersides of the upper arms. Never directly on the breasts. P may cause mood swings off cycle as the same as a woman off of her cycle. PMS, baby! Also the transwoman do not have the ovaries, cervix, and uterus that gives off the other little hormones that cis women have that may be a factor in breast cancers. A different analog here. My Dr. took me off of P a year ago due to the alleged ineffectiveness and the edema associated with the foot problem. No changes since.
Joelene