I would never stick a needle in there. No way, no how. However, after I inject in my thigh I sometimes unscrew the needle after injection, push up the few drops that get stuck in the vial, and apply it topically to that area. Does it increase my size anymore than it would if I didn't do it? I don't know but might as well do it instead of throwing it away. I've never had any side effects from doing so but if anyone else is thinking of doing the same it's at your own risk.