I have cleared all the hurdles so far and received my initial low-dose prescription of testosterone blocker today to ease me into my HRT regimen. It is the normal spironolactone tablet and smells minty. Taste I don't know yet because I just rather unceremoniously swallowed it with my mid-day coffee. Celebration will wait for when I actually notice any effects. The reference sheet that came with it says "Even though you may not feel the effects, this medication takes effect within a few hours." It also says it is more effective when taken with food but my doctor said it didn't matter when I took it. The dosage will be upped rather quickly over the next two to three months, barring any problems, and I will have to have bloodwork done at every major dosage change.
Possible side effects were listed as follows:
- occasionally, it may cause breast development in men (Yippie!)
- it may cause nausea or, rarely, vomiting
- it may cause your breasts to feel swollen and tender (This better not tease me!)
- it may cause headaches
- it may cause cramps
- it may alter your sense of taste (

)
Not mentioned is the likelihood of frequent need to urinate although as a diuretic I guess you're just supposed to assume this anyway. (Right now my morning and mid-day coffees are ready to 'drain' but that isn't the meds kicking in yet.) It also doesn't mention possible loss of spontaneous erections or dizziness, both of which my doctor noted. She told me to avoid standing up quickly after sitting or lying down for a while to avoid potential lightheadedness. She also said I might feel generally more tired.
The real bonus was learning my employer's health coverage will likely pay 80% of the costs of the hormone prescriptions and a portion of the dispensing fee. I also have a drug card from them so I don't have to file manual paper claims. My first month's worth of Spiro cost $6.75 and I can't see how this would increase much with the phased increases in dosage. They will even cover estrogen patches if I have to switch to them from pills later.
The part that sucked was when the pharmacist called me "Sir" without any hesitation. Really!?! And I thought I was looking gorgeous today!
I'd like to hear from any of you with experience on Spiro alone how it felt starting out and over the first couple months. What happened and what didn't? How quickly did you notice certain effects? Did anything affect your ability to work? Everyones' situations will be slightly different but there should be some consistent common ground.