Hey everyone,

I just wanted to know if it matters whether you split dosages ir take them all at once?   I used to do twice a day, but my dise was increased to 3 times a day.  I'd rather not do the math and find an estrogen lunch break everyday.  So does it really matter if I take it all at once.  Thanks

I'd say it matters, in the sense that the more pills you cram in the same period of time, the more work you are giving to your liver to process everything. And that's never a good thing on HRT

Yes, it does matter

Don't want to sound like a scolding mother, but the dosage regimen is set up the way it is for good reason

Not following the proper regimen as prescribed is very dangerous and could do you more harm than good

Just want you to be healthy and happy dear

Good advice, listen to your sisters sweetie!

Thanks everyone, 

I appreciate all the feedback.  I'll do the three times a day thing, but it sucks.  I'm always forgetting what time to take things and adding a third period is a lot.  Especially, when my breaks at work are already hectic.  However, I'll find a way.  On the positive side, it's more estradiol, so it's a rewarding chore even if it's annoying.