Just to give my input on the necessity of taking your medications on time; I almost never had headaches (or migraines) while being punctual with E. It's when I (deliberately, because I previously stupidly overdosed) went off spiro (and that in turn let the T do it's work) and it took only a couple of hours to note the changes. The carelessness, the numbness of feeling, and I even became
more scatterbrained in that short period. Whoever said women are scatterbrained??

And also one possibly useful fact, that the most studies link brain fog issues with long-term spiro usage. In users with shorter than six months usage, the occurrence in 100 patient sample is one-digit number, whereas in users of more than six months the figure is much higher. I remember those issues having started somewhat after a six month-mark. And more intensely as I entered the month of eight. I wish there was an alternative to spiro, even though it's relatively safe there are some serious drawbacks.