Hey guys has anyone here had rashes pop up on their body from hrt?

I'm currently taking estradiol valerate injections + spirolactone and I have this weird red spotted rash on both my ankles and it's super itchy lol. I had this happen before and thought it might have been an allergic reaction to the cottonseed oil my estradiol valerate was suspended in so I switched to EV in castor oil and it went away and thought problem solved, but now it's back and worse then before. After doing some research I found that spirolactone can cause rashes on people but it's rare like only 1% of people experience rashes from it.

I'm afraid that if it is the spiro causing these rashes then my doctor will want to take me off of it even though I need spiro to lower my T. Not sure what to do here.   

Considering that there is more than one AA available, I  think a doctor would be just the person to ask.

Sorry, I'm on Spiro but fortunately no rashes. Sounds like the doc is the best person to ask, especially if it's worse than before.

I'm on estradiol valerate injections every other week an spirotone daily an have not had any problems with it. You need to talk to your Doctor about it.

I have a strange rash I've never had before? A month or so ago one ear became irriated & it took serious anitbodics to clear it up.  On spiro & patches.

Any one else have any adverse reactions to spiro??

HRT made me allergic to nickel,I used to wear cheap watches and jewellry for years with no problem before HRT.Check you haven't a nicke lallergy

I also have a reaction to spiro on my calves. It comes and goes for me. Hopefully i'll be off spiro soon!

Quote from: big kim on November 24, 2013, 05:46:35 AM
HRT made me allergic to nickel,I used to wear cheap watches and jewellry for years with no problem before HRT.Check you haven't a nicke lallergy

Thank you!!!. That might be it. The rash is around my neck mostly on the back side. I have been wearing cheap jewelry.

If there's even a chance that it might be an allergic reaction to the medications, you do want to contact a doctor - it's rare, but sometimes those can be serious or even lifethreatening. Of course, it also might be fine and controlled with occasional Benadryl. Knowing the difference is what the experts are for.

(FrancisAnn : Anything that needs antibiotics to clear up is an infection, which by definition means it's not an allergic reaction. Could be coincidence?)

Jenna Marie, Thanks. I do not think my rash has anything to do with spiro. Think I know the cause, it's clearing up.

Quote from: LordKAT on November 23, 2013, 06:24:45 PM
Considering that there is more than one AA available

Really? The only other one I know of is cyproterone acetate which is not available here in the US.

http://livertox.nih.gov/Anti-androgens.htm


Cyproterone, despite evaluation in many clinical trials, has yet to receive FDA approval for use the United States, largely because of its potential for hepatotoxicity.  In contrast, flutamide, nilutamide and bicalutamide are now approved and in general clinical use for therapy of prostate cancer.  The largest and longest clinical experience has been with flutamide which has been shown to produce clinical remission in patients with prostate cancer, and is also used in hyperandrogenic states including acne and hirsutism.  Nilutamide has been extensively studied and is indicated for use in combination with surgical castration for the treatment of metastatic prostate cancer and is recommended to be started at the time of orchiectomy.  Unlike flutamide, nilutamide has not been evaluated in detail as therapy of hirsutism or acne.  Bicalutamide, the most recent antiandrogen to be approved for use in the United States, is also used in therapy of prostate cancer, but has not been approved for use in nonmalignant hyperandrogenic states.