I haven't had leg cramping or depression. I have had a bit drier skin; though, i hear it's just a winter thing. I had blackheads on my nose for the longest time pre-HRT, but those have disappeared. I'm also happy like 24/7 now, with occasional bouts of crying for what would seem like no reason at all (usually caused by a sweet moment in a movie or when reading a sad article, lol).
With estrogen expect softer skin, breast development, fat redistribution to thighs & other parts, among other changes. In my opinion, the changes are all good. I'm happy I started.
I've been on Finasteride and Spiro for about 6 months, and estrogen patches for about a month and a half.