Hey every one. Recently I had been given the option to change from spirolactone to Zoladex. if you have not looked into Zoladex it prohibets the production of luteinizing hormone releasing hormone, that is the hormone that signals the production of testosterone in men and oestrogen in women.

after talking to a DR that i work with. one of the benafits of working in an ER. I have found out that it is fully effective in 2-4 weeks. taking testosteron levels from the 500's to the teens.

the main question i have is would you if you could? and should i?

I'd be asking about its side effects and how it would interact with estrogen hormones. A benefit (at least as I understand it) is that Spiro is a diuretic so counters the tendency of the E to retain water. Of course, Spiro also reduces blood pressure so this other stuff could be good for people with low BP.

I know a few people who have taken it and all seemed happier than with spiro, but the thing is, most people don't really like spiro's ancillary effects. I know lots more people who take flutamide, androcur or bicalutamide when looking for an alternative to spiro. Now, I don't really know all that much about the specifics of zoladex (goserelin acetate) but, it would worry me a bit, that these other alternatives seem more popular than it. That isn't saying that it is good or bad, but I would want to try and figure out why it isn't a more common choice.

To be totally fair though, I don't understand why spiro is the most common choice since for me at least, it started to give really annoying side effects with it's diuretic effect and outright dangerous effects from the lower blood pressure. Lots of people could get really hurt if I were to faint at my job.

Quote from: Hikari on March 30, 2014, 03:20:00 AM
I know a few people who have taken it and all seemed happier than with spiro, but the thing is, most people don't really like spiro's ancillary effects. I know lots more people who take flutamide, androcur or bicalutamide when looking for an alternative to spiro. Now, I don't really know all that much about the specifics of zoladex (goserelin acetate) but, it would worry me a bit, that these other alternatives seem more popular than it. That isn't saying that it is good or bad, but I would want to try and figure out why it isn't a more common choice.

To be totally fair though, I don't understand why spiro is the most common choice since for me at least, it started to give really annoying side effects with it's diuretic effect and outright dangerous effects from the lower blood pressure. Lots of people could get really hurt if I were to faint at my job.

I think spiro os so comon due to the cost and that is also why zoladex isnt as populor. it over 400 every 3 months most insurance wont cover inless absilutly nesisary. Through the VA it is free for me.

Quote from: Ms Grace on March 30, 2014, 02:02:18 AM
I'd be asking about its side effects and how it would interact with estrogen hormones. A benefit (at least as I understand it) is that Spiro is a diuretic so counters the tendency of the E to retain water. Of course, Spiro also reduces blood pressure so this other stuff could be good for people with low BP.

That DR who told me how fast it worked read it off the information that he has access to specificly for HRT for transgender. There is no drug interaction. as for the side efects supprisingly few.

If I could and it was free, I would definitely take it over Spiro...much less side-effects, one injection every few weeks or every 3 months (?). 

Hey Sheala!
       I'm hoping you're still an active member and see this because I would definitely like to talk to you! I'm currently dealing with the VA (Veteran Affairs) right now and was curious as to if that's what you were referring to? I tried to find a way to message you, I just don't know how. =p