I have been on a roller coaster in the 3 1/2 years of HRT using the Spiro component and some of the effects coming back on are similar as first used. At first there was the breast tenderness at 2 1/2 weeks on E and Spiro with some tenderness and a little pain. That has not occured this second time, but the breasts are getting close to the size before coming back on Spiro. The Spiro was removed for 6 months with the E still being taken due to the flushing of the sodium and the other kidney items plus the pain relievers used for the peripheral neuropathy. The T level went up as well as my PSA (prostate) reading shot up.
Both times, the usual body hair and beard thinning after one month. Softness of the skin and with the soles of the feet more evident this time after using the Lamisil, an antifungal pill used. About 35 years with the fungus on the soles of the feet misdiagnosed and after one month on the stuff, fungus and callouses gone. Both times, yet, the increase of muscle mass and body strength. My doc says that is unusual, but not unheard of. This after another winter in bed in pain. The pain relievers stopped working. The gardening, the large 1 ton telescope mount repair, and today with the digging around the foundations of the out buildings at my club's site for rodent abatement. All of these help with the recuperation. The guys at the site were keeping up with me today! We are in the same age group, 60's.
Joelene