I know not applicable to Americans due to no approval
But for Canadian girls here is my experience with cypro

I was on the standard dose of Spiro and it almost burned
Out my kidneys. Luckily I saved them in time and dropped down.
As I spoke to my ts specialty care doctor in Vancouver I realized
It was time for orchiectomy or the feared cypro.
I chose cypro and my T is suppressed down to
.15 so it works. No renal issues what so ever. And apparently if
You stay on cypro long enough your factories can be so damaged from
The cypro they will never produce T again.

edit NO DOSAGES/DIY HRT TALK