From my first two weeks on blockers I remember being incredibly tired and having almost uncontrollable taste for sweets.
And during the first two weeks when estrogens were added... Well, that's when things started to get quite wild. I'm glad the nipple sensitivity went to acceptable levels only two weeks later :-) .
Just the fact I constantly felt like vomiting after the first injection for 5 days and then for 2 days after the second injection was really annoying. That didn't repeat fortunately.