I've wondered about this, the physical vs the emotional aspects of reorientation. Anecdotally, I had heard many cases of a change, and had been told when I started to transition that outcome regarding orientation really was anyone's guess. There is research revealing that estrogen influences how female brains repair and rewire more easily than male, and we know that on HRT over a period of time every cell is more or less "reprogrammed." I've wondered whether the repair also sparks a slow reworking, and whether it accelerated or magnified any tendency over time. Attraction is so emotional as well, and I wondered if people "let loose" on HRT and especially post transition, and that they become less inhibited to explore an attraction. I also wondered whether the research on brain differences done postmortem and showing correlation of female brains and MTF transsexual brains was performed on women who had long been on HRT, and whether that treatment had any influence. This research suggests some impact on the orientation alone, which even without HRT isn't well understood, but as Hans asks, is there a study for a larger sample?