I never consider hormones "medications", so I don't disclose that when I donate blood. And as for it disrupting your hormone balance, I doubt it. It doesn't happen to cisgendered people, so why would it happen to us?
As far as risk factors, they're in a tizzy because they don't know whether to ask you the male or the female questions, none of which actually address risk anyway. I answer the male questions, but if I knew I was at risk for any reason, like unprotected sex, sharing needles, or anything, then I wouldn't donate.
It pisses me off that their so-called risk reduction bears little to no relation to what they are claiming to accomplish.
Dennis