What separates me...?
A unique combination of DNA, likely not shared by anyone else on the planet.
The unique 'settings', tendencies and biases the DNA causes.
The fact that anything I experience with another person at the same place and time is merely similar, never identical.
The people I've encountered and the moments and ways I've encountered them are different than the people others have encountered and the moments and ways of those encounters, even if we're all in the same place and at the same time.
A 30th of a second (minimum) delay between a stimulus impinging on a receptor (light/eye, sound/ear, taste/tongue, touch/skin, odor/nose,) that guarantees I'll never experience reality except through a delay and the imperfections and distortions of my transducers, and only deal with a facsimile of reality.
The realization that I'll never pay my money and 'be John Malkovich' (remember the movie?) or any other celeb or person I admire -- I can only be me.
That being said, It's amazing we humans even connect at all;

Karen