My level was high when I started, with a low dose that my doc then lowered a bit more. It stayed high for another couple of months, then dropped into the normal range. The only symptom I had was some nipple soreness in the first month or so. After that I seemed OK with the high level, and I have mixed feelings about its having tapered off -- things are changing pretty slowly as it is. On the other hand, that little vial lasts a long time with such a low dose...