Uhh what? First off it doesn't require the highest dosage, in fact you should probably get to mid level dosage. After a week you should feel calm and happy. Like within a couple months nipples start tingling and swelling of the nipples, followed by breats growth. I'm at an A cup and I'm at 6 months. My face and skin have softened dramatically, as well as better defined in the face. After about 3 months of E oral twice day and Spiro twice day, my doctor put me on E IM injections and still same spiro regimine. Though my levels when tested was 905 estrogen level and 25 Testosterone level. I feel my E is to high and need to come down a bit, as my feminizing seems to have come to a stop. No breast, face, and body difference. But I so far have had good results. A little weight gain, hips, butt, A cup, decent facial, and soft skin. I feel girlier, my mannerisms changed to female. The voice naturally I have to keep working on. It's decent and passable but I demand better lol. It's probably because I sing beautifully and speak like ..meh..ok.
edit out dosages Tos 8.