I work for a large non-profit that employs people across the borders of many states here in the US. I have worked pretty hard to put some things in place at my place of employment. Granted, I am still in transition and these things also benefit me, I did make sure that those benefits would be available to all employees of my employer.
*Transitioning openly and being very open with people at my work so they might better understand the trans* struggle (At least from my perspective).
*Convinced my workplace to adopt a trans-friendly health insurance policy (There is currently no coverage for trans* things including HRT and therapy).
*Wrote a small part about pronouns and why they are so important for the HR department to use in quarterly reports.
I am a very skilled part of the IT team so I used their dependence on my skill set to gain leverage (I threatened to quit and go to the media/civil rights groups). Those two things hit hard as immediately they implemented the thing about pronouns in the HR newsletter. As for the health care coverage, that begins when we change to this coming year's plan

This feels like small feats compared to the efforts other people have made towards the advancement of equality, however I can rest assured that my efforts at least have helped the ~1000 employees of my workplace. I would love to try and figure out some larger scale stuff.