OF COURSE it doesnt matter as far you have found hapiness.
I respect everyone's opinion no matter what it is. But even Im not a doctor, I have an argue here.
With an exception of cases, such as Myarkstir's, where they know exactly what happened, the bad feelings one experiences because his/her "I" looks at the body and realizes they dont match, are the reasons or the results? Maybe the results because of the imprisoned woman/man (aka "I") inside the wrong body?
You may all be confused as I use sometimes to mess with my english as its not my first laguage. I just think of something more simple to give you my point.
Imagine the human race as we all know but with a single difference. No eyes. We dont have eyesight, we are blind. People with such diversities, just like the beautiful lady ImagineKate suggested, would feel, for example, dysphoria? The mismatch? Even the people like Myarkstir, where the body's chemistry is the cause?
My point of my point (lol) is that the "I" looks at the body, disagrees with what it sees, and as all we know, the brain "obeys" to the consciousness and the result is the exudations of some chemical fluids which determine our mood, or even make us feel the dysphoria.
But again, I totally understand when some of you say that you dont care for the "why", I wouldnt too if I were in your position. This is just a philosophical quest. I like it. Im greek

Btw, thank you all for your contribution