I've been on estogen now for nearly a year and it is without a doubt the most powerful medicine I have taken. This stuff is like the medicinal equivalent of an atomic bomb. It has literally changed me from the inside out. Not only has it changed me physically but mentally as well and not in subtle way either. The changes have been profound. I don't even think the same way. My sense of taste and smell are even different. Well I just wanted to share that. I hope others here have the same results.