So I've been on a LOW dose of estrogen for three days and actually my leg started being achy the first day I took it... my calves/shin areas are prone to getting sore anyway.. haha! But I'm a bit of a "hypochondriac" literally, and have OCD and can worry to the point of panic about almost anything.. I know it's a "call your doctor" thing or something, but also, I just wanted some reassurance that it IS very unlikely to be anything scary being so soon after starting and having such low doses.. anyway.. this is my least fav part about HRT lol! My own anxiety about DVT and such. lol!